Green’s Dictionary of Slang

loco v.

[loco/loca adj.]

(US) to drive mad.

[US]A.H. Lewis Wolfville 228: It locoes him an’ makes him f’rocious.
[US]‘Sing Sing No. 57,700’ My View on Books in N.Y. Times Mag. 21 May 7/4: The clever way that pie-face discovered the pirates’ hidden cash certainly had us locoed.