Green’s Dictionary of Slang

1. (orig. US milit.) tough shit, often used ironically or mockingly as well as sympathetically; also as adj.

1944		N. Mailer letter 30 Apr. in Selected Letters (2014) 17: It’s about time I gave you some Army terms and what they mean. The most common expression is ‘t.s.’ otherwise known as ‘tough shit’.
1945		in T. Shibutani Derelicts of Company K (1978) 308: If you fuck off, it’s TS; he’ll throw the fuckin’ books at ya.
1948		(con. 1944) N. Mailer Naked and Dead 21: If there’s a man here suddenly discovers he’s left anythin’ behind, that’ll be just t.s.
1953		L. Uris Battle Cry (1964) 47: Get a T.S. chit from the chaplain.
1963		F. Kohner Affairs of Gidget 86: T.S., as we say so aptly in Cascadia.
1989		H. Rawson Dict. of Invective (1991) 353: Euphemized, abbreviated form, T.S.

2. (US Und.) Times Square.

1963

in T.I. Rubin Sweet Daddy 46: T.S. [...] No, not tough shit. Tough shit too, but I mean Times Square.