Green’s Dictionary of Slang

f.o.! excl.

[abbr. fuck off! excl.]

(US) go away! leave me alone!

[US] ‘Imaginary Diseases’ in AS XXII:4 Apr. 305/1: f-o-itis. Pronounced eff-oh-itis; meaning ‘malingering’; based on initial letters in the manner of snafu.
[UK]Private Eye 6 Nov. 1: F. O. the lot of you!
[US]P. Munro Sl. U. 82: F.O.! Get out of here! You make me sick!