Green’s Dictionary of Slang

roofie n.2

also rophy, ruffie, ruffle, rufy, wolfie
[the drug, which causes users to appear drunk, is allegedly popular as a new form of knockout drop, prob. used to facilitate a number of rapes]

[1980s+] (drugs) Rohypnol, a strong sedative; often in pl; also as v. to spike someone’s drink with Rohypnol.