Green’s Dictionary of Slang

red and blue n.

[the colour of the pills]

(drugs) Tuinal, a barbiturate.

[US]R.R. Lingeman Drugs from A to Z (1970).
[US]E.E. Landy Underground Dict. (1972).
[US]D.E. Miller Bk of Jargon 338: reds and blues: Barbiturates (Tuinals).
[US]ONDCP Street Terms 18: Red and blue — Depressants.