Green’s Dictionary of Slang

1. (US police) to stop and search.

1986

Chapman NDAS.

2. (US) to have sexual intercourse with.

1936		D. Stivens Tramp and Other Stories 86: She won’t take on anyone in the town.
1947		I. Shulman Amboy Dukes 30: I took on eleven of you guys.
1959		W. Brown Teen-Age Mafia 71: Dum Dum wanted first crack at the girl and thought Pico was planning to take her on.
1966		H.S. Thompson Hell’s Angels (1967) 199: She’s taking on fifteen guys in the back of a pickup truck.
1989		(con. 1956) P. Theroux My Secret Hist. (1990) 6: She was a real tramp. She once took on six guys.

3. see take v. (1)