Green’s Dictionary of Slang

V and X (store) n.

[Lat. V, five + X, ten, i.e. a ‘five and ten cent’ store]

(US black) a corner store.

[US]R. Mulvey ‘Pitchman’s Cant’ in AS XVII:1 Pt 2 Apr. 93/2: v and x. Any five-and-ten-cent chain store.
[US]Z.N. Hurston ‘Story in Harlem Sl.’ in Novels and Stories (1995) 1010: V and X: five-and-ten-cent store.