Green’s Dictionary of Slang

m.f.w.i.c. phr.

[abbr.]

(orig. US milit.) a term of abuse, motherfucker who’s/what’s in charge.

D. Cragg Lex. Militaris 285: MFWIC. Motherfucker what’s In Charge [HDAS].
Dr. Dobb’s Journal Mar. n.p.: Frank Grossman, the MFWIC (‘main fellow who’s in charge’) at Nu-Mega, was demonstrating BoundsChecker for Windows [HDAS].