Green’s Dictionary of Slang

1. (US) the execution chamber.

1945

R.L. Bellem ‘Poison Payoff’ Hollywood Detective Dec. 🌐 But that would have made you a murderess and sent you to the smoke-house.

2. (US) a privy [the smoke rising from the discharged urine into the cold air].

1949

Monteleone Criminal Sl. (rev. edn) 214: smoke house [...] a privy; a rest room.

3. attrib. use of sense 2.

1951		(con. 1920s) S. Longstreet Pedlocks (1971) 149: Smokehouse stuff, huh?
1953		S. Bellow Augie March (1996) 225: Telling smokehouse stories while the goofy audience waited for the naked star to come out and begin the grinds.

4. (US drugs) a house or apartment where crack cocaine is sold and used.

1993

E. Richards Cocaine True 42: It’s a smoke house. It’s always crowded.

5. see smoker n.¹ (2d)