Green’s Dictionary of Slang

(US) a sexual pervert.

1969		H. Ellison ‘A Boy and his Dog’ in Beast that Shouted Love (1976) 181: With all the twisties in the Metropole, I didn’t think a chick would chance it. Be a toss-up who’d tear her apart first: the boxers or the straights.
1990		S. Morgan Homeboy 25: Twistos, weenie wavers, panty sniffers . . .