Green’s Dictionary of Slang

1. (US) an alcoholic drink.

1867

W.H. Dixon New American I 191: Eye-opener, fix-ups, or any other Yankee deception in the shape of liquor.

2. see fix n.² (1)

3. (drugs) an injection of a narcotic drug.

1930		M. West Babe Gordon (1934) 13: He wanted a fix-up of coke.
1949		Monteleone Criminal Sl. (rev. edn).
1959		J.E. Schmidt Narcotics Lingo and Lore.
2017		D. Winslow The Force [ebook] Maybe he can sell it [...] score a fix-up shot.