1. [1950s] (US, also skunkie) a bedwetter; also attrib.
2. [1960s–80s] a woman, esp. one who smells badly.
3. [1970s] (US) a black and white police car.
4. in drug uses.
(a) [1980s+] (drugs, also skunkweed) an exceptionally strong variety of marijuana (often grown in the user’s home) with up to 30% tetrahydrocannabidinol (THC) content, thus intensifying the effects from the merely stimulating to those of such hallucinogens as LSD; thus superskunk, an even stronger variety.
(b) [2000s] (US black) poor quality marijuana.
(c) [2000s] heroin.