Green’s Dictionary of Slang

(US) to move around from place to place.

1838		J.C. Neal Charcoal Sketches (1865) 66: The three little Timkinses, who could locomote, went scrabbling, in different directions.
1847		W.T. Porter Quarter Race in Kentucky and Other Sketches 83: He throws the galls in, and a bed too in the hay, if you git too hot to locomote.
1914		E. Wittmann ‘Clipped Words’ in DN IV:ii 139: locomote, from locomotion. To walk.