Green’s Dictionary of Slang

blow someone’s head v.1

also blow someone’s skull
[SE blow, explode + head/skull]

1. (US, orig. drugs) for a given drug to intoxicate someone.

[US]E. Hunter ‘Vicious Circle’ in Jungle Kids (1967) 32: Here man [...] Blow your skull.

2. in fig. use, to disconcert.

[US]M. Baker Nam (1982) 77: What blew my head was what they did to calm me down.