Green’s Dictionary of Slang

cuckoo n.1

[SE phr. cuckoo in the nest, denoting the oddness of such an individual]

1. [late 16C–early 18C] a cuckold [the cuckoo lays its eggs in another bird’s nest].

2. [late 16C+] (also coo-coo) a fool, an eccentric, a silly person.

3. [1920s] (US) something foolish, a failure.

In compounds

cuckoo academy (n.)

[1960s+] (US) a psychiatric institution.

cuckoo bird (n.) [bird n.1 (3a)]

[1940s+] (US) an eccentric, a mad person.

cuckoo farm (n.) [farm n.1 ]

[1960s+] (US) a psychiatric institution.

cuckoo house (n.)

[1930s+] (US) a psychiatric institution.

cuckoo juice (n.) [juice n.1 (3a); its potency sends one crazy]

[1960s–70s] (US) strong liquor.

cuckoo’s nest (n.)

[1960s+] (US) a psychiatric institution.

SE in slang uses

In compounds