Green’s Dictionary of Slang

an effeminate-looking man.

c.1786		Grose Classical Dict. of the Vulgar Tongue ms. additions n.p.: Twidle-poop, an effeminate looking fellow.
1796		Grose Classical Dict. of the Vulgar Tongue (3rd edn).
1811		Lex. Balatronicum.
1823		Egan Grose’s Classical Dict. of the Vulgar Tongue.
1834		‘Jack Downing’ Andrew Jackson 25: To look at him you’d think he was a mere twiddlepoop.