Green’s Dictionary of Slang

1. (US) to have sexual intercourse.

[1597		T. Deloney Pleasant Hist. of Jacke Newberie (1633) xi M: Sir George having received this answer was wonerous woe, cursing the day that ever he medled with Joane, whose time of deliverance would comme long before a twelve Moneth were expired to his utter shame].
[1612		N. Field Woman is a Weathercock II i: wag.: I am with child by you. pen.: By me? Why, by me? A good jest [...] Why, do you think I am such an ass to believe nobody has meddled with you but I?].
1942		in G. Legman Limerick (1953) 131: A hermit who lived on St. Roque / Had a lily perfected to poke. / He diddled the donkeys / And meddled with monkeys.
1975		G. Underwood ‘Razorback Sl.’ in AS L:1/2 62: meddle vt [...] 2: Have sexual intercourse with.

2. (US black) to molest sexually.

1984		A. Sample (con. 1920s) Racehoss 17: ‘I wisht you’d make them ol boys a’ your’n stop meddlin me.’ [...] Big Auntie asked with indignation, ‘meddlin’ you how?’ ‘They puttin they hands up under my dress, pinchin my titties an stuff’.
1984		A. Sample (con. 1940s-early 1950s) Racehoss 113: ‘Nonea them old crap nigguhs don’ mess with you do they?’ ‘Nawww, if Mama wuz to ketch one uv ‘em meddlin me she’d run his ass way from here’.