Green’s Dictionary of Slang

1. (US drugs) to stop taking a narcotic drug.

1910

Wash. Post 3 July 3/1: Listen ter the dope [...] Why, he couldn’t even taper down, let alone break off.

2. (US black) to disengage oneself from a confrontation.

2000

Ebonics Primer at www.dolemite.com 🌐 break off Definition: used as a command to another combatant before a fight as one last chance to leave before the fight begins. Example: Wha’? You dissin’ my ho’? You better break off foo!