Green’s Dictionary of Slang

a blasphemous excl.

1695		Congreve Love for Love III xv: Flesh, you don’t think I’m false-hearted, like a Land-Man.
1706		Farquhar Recruiting Officer II iii: Flesh, I’s keep on my nab!
1707		J. Shirley Triumph of Wit (5 edn) 194: The cully flams Flesh rumly [The Fellow Cants very well].
1707		Humours of a Coffee-House 10 Sept. 23: Flesh and Nouns Sir! [Ibid.] 3 Oct. 29: Flesh and Eels, Doctor!
1728		Vanbrugh & Cibber Provoked Husband I i: Flesh! I thought we should never ha’ got hither!