Green’s Dictionary of Slang

hand-to-hand adj.

1. (drugs) of drugs, delivered immediately; thus as n. and v.

[US]H. Braddy ‘Narcotic Argot Along the Mexican Border’ in AS XXX:2 87: HAND TO HAND, adj.phr. Delivered immediately.
[US]R.R. Lingeman Drugs from A to Z (1970) 109: hand to hand, to To transfer narcotics at the point of sale, as opposed to ‘drop’, where the buyer picks them up after paying the money.
[US]ONDCP Street Terms 11: Hand-to-hand — Direct delivery and payment.
[US]R. Cea No Lights, No Sirens 103: He did the hand-to-hand dealings in the street, so fast that I actually clocked him slinging Shah’s potent boy to twenty junkies in less than a minute.
[US]G. Pelecanos Drama City 191: The jump-out squad got me on a corner in my own neighborhood, doin’ hand-to-hands.
[US]Codella and Bennett Alphaville (2011) 4: We size up everybody - the steerers calling brands, the dealers making hand-to-hands, and the junkies crawling in feeling bad.

2. in non-drug contexts, direct person-to-person payments.

[US]R. Cooley When Corruption Was King 197: I put together a list of all the judges I had paid off—either ‘hand to hand’ or through a conduit.

In compounds

hand-to-hand man (n.)

(drugs) transient dealers who carry small amounts of crack cocaine.

[US]ONDCP Street Terms 11: Hand-to-hand man — Transient dealers who carry small amounts of crack.