Green’s Dictionary of Slang

1. opium.

1952

(con. 1920s) G. Fowler Schnozzola 60: This was a song about an opium addict. Under the influence of a drug known as Chinese tobacco, or Wyoming ketchup, Willie had a dream.

2. (US) alcohol.

1933

W. Winchell On Broadway 23 May [synd. col.] A heavily saturated with Wyoming Ketchup Pete-man was doing a little chesty chatter before a group of novices in the same racket.