Green’s Dictionary of Slang

scotched up adj.

(US) drunk.

1931		D. Runyon ‘Lillian’ in Guys and Dolls (1956) 244: She takes up with Gregorio, the Ginney bootlegger, who keeps her well Scotched up all the time.
1938		D. Runyon ‘The Big Umbrella’ in Runyon on Broadway (1954) 553: By this time he is slightly Scotched up, and he always likes to have a little moral support when he goes home Scotched.