Green’s Dictionary of Slang

(drugs) the mild tranquillizer Valium.

1981		cited in Spears Sl. and Jargon of Drugs and Drink (1986).
1996		R. Rendell Keys to the Street 283: He needed something to bring him down. Yellow jackets or Vs.
2001		ONDCP Street Terms 22: V — The depressant Valium.
2001		D. Looser Boobslang [U. Canterbury D.Phil. thesis] 198/1: V abbr. a Valium pill.