1. [1920s+] the vagina.
2. [1920s+] (also couse) a woman (usu. promiscuous or unattractive); by ext. a prostitute.
3. [1940s+] (also kuse) a term of abuse, i.e. a cunt n. (5)
4. [1950s] a passive/effeminate homosexual.
5. [1960s] (US gay) a lesbian.
6. [1980s] a term of address to a sexually exciting woman.
7. [1980s+] vaginal secretions.
8. [1990s+] sexual intercourse with a woman.
9. attrib. use of sense 8.