Green’s Dictionary of Slang

kooked-up adj.

[kook up v.]

(US) crazy, eccentric.

S. Alinsky in Harper’s Mag. June 44: In this kooked-up irrational world, you really have to have a sense of humor to survive [HDAS].
The Slime Society You Can’t Do That On Television 🌐 First memory would have to be my watching it on TV before I even got involved and thinking just what a CRAZY bunch of kooked-up kids those guys were.