Spital whore, n. — Green’s Dictionary of Slang

Spital whore n.

also Spital lady, Spittle sinner, Spittle whore

[Spitalfields, a tough East End area of London + SE spital, a hospital (and origin of the district’s name), thus underlining the physical perils of being a prostitute]

a prostitute.

1553		Respublica in Farmer Lost Tudor Plays (1907) V ix: Plain lady, smooth lady, sometime spital lady.
1580		Baret Alvearie n.p.: Spittle whore, a very common whore [F&H].
1596		T. Lodge Wits Miserie and the Worlds Madnesse IV 96: He is the secretary to the spittle whores.
1608		Dekker Honest Whore Pt 2 (1630) V ii: Doe you take me for a base Spittle whore?
1613		Middleton Chaste Maid in Cheapside V i: Of all wittols, Be thou the head. Thou, the grand whore of spitals.
c.1618		Massinger & Field Fatal Dowry (1632) III i: I will rather choose a Spittle sinner Carted an age before, though three parts rotten.