Green’s Dictionary of Slang

1. a doctor, an apothecary.

1622		Massinger Virgin-Martyr IV i: Thou stinking clyster-pipe, where’s the god of rest, Thy pills and base apothecary drugs Threaten’d to bring unto me.
1661		A. Wood Life of Anthony à Wood I (1772) 167: John Haselwood, a proud, starch’d, formal and sycophantizing Clister-pipe, who was the Apothecary to Clayton.
1785, 1788, 1796		Grose Classical Dict. of the Vulgar Tongue.
1811		Lex. Balatronicum.
1812		Spirit of Irish Wit 104: ‘He is only a lousy glyster-pipe, a mere foot soldier in the service of death’.
1823		Egan Grose’s Classical Dict. of the Vulgar Tongue.

2. (also glister-pipe) the penis.

1681		Character of an Ignoramus Doctor 2: [Titus Oates] has two or three Brawny Catch-Polelike Porkers to attend him, whose Posteriors he often taw’s, or (as Mother Creswel terms it) Flogg’s; and when he has rais’d his own Beastly Concupiscence, Tilts at ’em with his Nasty Clyster-Pipe.
[1700		‘Enfield Common’ in Playford Pills to Purge Melancholy II 270: No one was near us, to over hear us, / at length I said I’d put my Pipes in Tune, / to give a Glister, with that I kiss’d her].
1835		‘The Ladies Doctor’ in Secret Songster n.p.: My glister pipe is such a rum un, / A better one never could wag – / And to ease a poor invalid woman, / I’ve two bolusses tight in a bag.