Green’s Dictionary of Slang

neigho! excl.

also nayboo! nayo! neighbo!
[? SE nay, no + bo n.1 (1)]

(US black) used to express disagreement.

[US]Cab Calloway New Hepsters Dict. in Calloway (1976) 258: neigho, Pops: Nothing doing, pal.
[US]D. Burley Orig. Hbk of Harlem Jive 144: Neighbo Pops—That’s out, Chu, no chance.
[US]Time 10 Feb. 12: Nayo boss—no, buddy, that’s wrong [HDAS].
Cosby Show [NBC-TV] Nayboo! Nayboo! [HDAS].