Green’s Dictionary of Slang

(orig. US) a lesbian.

[1927		E. Hemingway letter 15 Dec. in Baker Sel. Letters (1981) 268: Hearst’s have offered him 182,000 bots for a serial about Lesbians who were wounded in the war [...] Bumby is calling the thing lesbos Lesbos LESBOS].
1940		J.H. O’Hara Pal Joey 99: I tho’t to myself Lesbo.
1959		H. Ellison ‘Sally in Our Alley’ in Gentleman Junkie (1961) 119: Priscilla and Teddy, the lesbos on the second floor.
1969		C. Himes Blind Man with a Pistol (1971) 116: ‘One was a man; a good-looking man at that.’ ‘Man my ass, they were lesbos.’.
1972		B. Rodgers Queens’ Vernacular 125: lesbian [...] lesbo; lesby; les girls [...] lezbo.
1973		D. Ponicsan Cinderella Liberty 165: Women and police dogs? Sixty-nining? Lesboes?
1980		A. Maupin More Tales of the City (1984) 88: I’m not a lesbo.
1998		D. Clowes Ghost World 31: Maybe we should be lesbos!
2008		A. Wheatle Dirty South 96: Does that mean there’s lesbos and chi-chi men doing their shit.
2010		IOL News (Western Cape)19 Mar . 🌐 You can just see she’s a lesbo.
2015		I. Welsh Decent Ride 169: If it helps any, just think ay me as a lesbo, but wi a cock n baws.