blown up, adj. — Green’s Dictionary of Slang

blown up adj.

[SE blow, to explode + ? image of a bloated drunkard]

(US) drunk or overindulging in drugs.

1978		Eble Campus Sl. Apr. 1: blown up – drunk.
1996		Eble Sl. and Sociability 45: Overindulgers in alcohol or drugs are pictured as the objects of various kinds of destructive processes: explosion (blasted, blown out, blown up, bombed).