Green’s Dictionary of Slang

homegirl n.

[var. on homeboy n.]
(orig. US black)

1. (also homelady) a woman from one’s home town or neighbourhood.

[US]Alaska Citizen 28 Aug. 7/2: He passed up the home girls as though they were pikers.
[US]Lait & Mortimer USA Confidential 39: To some men, the experienced professional has a greater appeal than the simple home-girl.
[US]Eble Campus Sl. Sept.
[US]Eble Campus Sl. Mar. 6: homegirl – girl from one’s home town.
[US]K. Scott Monster (1994) 116: We got sweated by homelady here.
[Aus]Cypress Hill Sl. Gloss. [Internet] homegirl: neighbor.

2. in attrib. use of sense 1.

[UK]D.S. Mitchell Killer Tune (2008) 45: My home-girl pussy getting in the way of your OK ya ting?

3. a woman.

[US]E. Folb Runnin’ Down Some Lines 36: Generally neutral or negative designations, such as [...] brother and sister, homeboy and homegirl.
[US]Source Nov. 137: Every homegirl from Saved By The Bell is up in the cut.

4. a close female friend.

[US]T.R. Houser Central Sl. 28: home girl A girl friend.
[US]G. Tate ‘A. R. Kane’ in Flyboy in the Buttermilk (1992) 109: I tell homegirl the next García Márquez or Morrison is coming out of the Bronx. She looks at me like I must be on drugs.
[US]L. Bing Do or Die (1992) xiii: Four years ago I had not shared a burger and a coke [...] with a sixteen-year-old homegirl whose denim school notebook was covered with gang slogans.
[US]W.T. Vollmann Royal Family 632: I drank my homegirl’s methadone.
[Aus]Cypress Hill Sl. Gloss. [Internet] homegirl: [...] friend, follower of hip-hop.
[US]J. Díaz This is How You Lose Her 3: Magda only found out because homegirl wrote her a fucking letter.

5. a female gang member.

[US]L. Bing Do or Die (1992) 97: I ask if she was a homegirl at one time. She smiles at the question. ‘Yeah, sure I was. [...] I was hangin’, bangin’ and slangin’ with the best of ’em.’.
[UK]Guardian Guide 5–12 June 9: Buffy and her stake-wielding homegirls.