1. [late 19C–1940s] the chin, the face, the nose.
2. [1930s+] (drugs) a hypodermic syringe.
3. [1940s+] (US) anyone standing guard or leading the way [milit. jargon point, the man walking at the head of a patrol; ult. ranching jargon point, the front of a herd].
4. [1960s] a nipple.
5. [1960s–70s] (gay) any form of writing implement.
[1990s+] (US prison) to keep a lookout.
1. [1970s+] standing guard, keeping a lookout; thus run point, to take the lead.
2. [1990s+] alert, sharp, aware.
3. [2010s] (US campus) attractive, e.g. of a garment.
4. [2010s] (UK black) very important; first-rate.
SE in slang uses
[late 19C+] to have an advantage.
[late 19C] to permit an advantage to.
[1960s+] (US) to give a good impression, to ‘score’ with someone.
[late 19C+] (Aus.) to live by one’s wits, to take advantage by trickery and deception.