Green’s Dictionary of Slang

1. (US) an attractive young woman.

1919		implied in sweet patootie
1942		R.L. Bellem ‘Daughter of Murder’ Dan Turner – Hollywood Detective Dec. 🌐 Bradley had a heavy date that night with his sweet patootie, a blonde named Vicki Ellery.
1964		A. Hine Unsinkable Molly Brown 27: First time I ever got money from a patootie.
1972		(con. 1916) G. Swarthout Tin Lizzie Troop (1978) 132: Cochita, you’re just the sweet patootie I’ve been looking for.
1986		L. Heinemann Paco’s Story (1987) 64: Ah’d love to roll in da hay wit-cha, my sweetes’ little patootie.
1997		Eble Campus Sl. Fall 2: cutie-patootie – another word used for a person who is attractive or cute.
2016		C. James in Observer 30 Oct. 🌐 Just because some baroque narcissist in the Oval Office had declared atomic war [...] when the hottest patootie in the West Wing typing pool swerved away from the outstretched plea of his tiny hands.

2. (US) the penis.

1927

in Randolph & Legman Ozark Folksongs and Folklore (1992) I 322: I wish I was in Alabam’, / A settin’ on a rail, / My old patootie in my hand, / An a yaller gal by the tail.

3. (US, also rooty-patootie, tootie) the buttocks; the anus.

1959		(con. WWII) B. Cochrell Barren Beaches of Hell 42: Well kiss my patootie.
1967		E. Shepard Doom Pussy 23: You’ll get pinked in the patootie.
1974		(con. 1940s) E. Thompson Tattoo (1977) 70: You hear with your patoot, curlylocks.
1977		L. Heinemann Close Quarters (1987) 233: Fucken-A bet yer sweet tooties, El-tee.
1978		S. Longstreet Straw Boss (1979) 259: You bet your sweet patootie I am.
1987		S. King Misery (1988) 236: ‘But you already, hadn’t you?’ [...] ‘You bet your rooty-patooties I had.’.
1990		R. Campbell Sweet La-La Land (1999) 9: I cut off your dingus and shove it up your sweet patootie.
2001		(con. 1964–8) J. Ellroy Cold Six Thousand 377: ‘Tiger Kab packs a knockout punch.’ ‘Tiger Kab kicks Cassius Clay’s patootie.’.
2015		T. Pluck ‘Moody Joe Shaw’ in Life During Wartime (2018) 250: ‘The Entwhistles, they’re such pains in the patoot’.

4. an effeminate man.

1956

T. Thursday ‘The Big Squawk’ in Smashing Detective Mag. 15 Apr. 🌐 ‘Naturally,’ said the pet patootie, with his best snooty-snotty eyebrow raise.