Green’s Dictionary of Slang

set adj.1

[? SE set back]

conquered, defeated.

[UK]J. Ware Passing Eng. of the Victorian Era.
[US] ‘The Flyin’ U Twister’ in G. Logsdon Whorehouse Bells Were Ringing (1995) 99: He’s mean as they make ’em, and don’t you forget / He’s hurt a lot of twisters and never been set.

In phrases

get someone set (v.)

(Aus.) to bear a grudge against someone, to have a score to settle with someone.

[Aus](con. WWI) A.G. Pretty Gloss. of Sl. [...] in the A.I.F. 1921–1924 (rev. t/s) n.p.: set. Fixed; all arranged; adapted from ‘two-up’ in which it is used to indicate that the money staked by the spinner has been covered by other bettors [sic]. ‘Got him set’ – treating him unfairly through malice.
[NZ]N.Z. Truth 4 Feb. 5/4: His wife’s parents ‘had him set’ and would not permit him near the house.
[Aus]Baker Popular Dict. Aus. Sl.
have someone set (v.) [abbr. SE set down]

(Aus./N.Z.) to have someone marked down for punishment or revenge.

[Aus]Bulletin (Sydney) 8 Dec. 20/1: The sportsman who sat on my left conveyed his impression of the youth in a brief whisper – ‘Mug! [...] Solly has him set. Just you watch how he’ll pal up to him for a little business.’.
[Aus]C.J. Dennis ‘The Play’ in Bulletin (Sydney) 16 July 47/1: ’Is cliner’s push – wot’s nicknamed Capulet – / They ’as ’em set.
[UK](con. WWI) Fraser & Gibbons Soldier and Sailor Words 254: Set, To Have Someone: To get the better of: to take at a disadvantage: to get a man convicted.
[US]J.A.W. Bennett ‘Eng. as it is Spoken in N.Z.’ in AS XVIII:2 Apr. 90: ‘To have a set on or against someone’ represents a conflation of the old-established ‘to have a down on’ and the Australian ‘to have (a person) set’.