Green’s Dictionary of Slang

something or someone annoying.

1974		R. Stone Dog Soldiers (1976) 55: It must have been some drunken piss-off.
1985		‘Thommo’ Dict. Aus. Swearing & Sex Sayings 12: A PISS OFF—Intense annoyance.
1983		Totally True Diaries of an Eighties Roller Queen 🌐 2 Dec. What a piss off. I’ll have the same lunch as that asshole Glenn.
1997–2002		Alt. Eng. Dict. 🌐 piss off (complex noun) thing or person that causes one to be angry.
2002		A. Duff Jake’s Long Shadow 63: Ryan could get ugly when he was drunk, not always but enough times to be a piss-off.