1. [late 19C+] odd, bizarre, unnerving.
2. [1960s+] (drugs) hallucinogenic, psychedelic.
3. [1970s] (drugs) strong, powerful.
4. [1980s] nervous.
[1980s+] (US) weird, bizarre.
[2000s] (US) to cheat, to deceive.
[1990s+] an eccentric; also used as a term of affection.
[1960s] a person who either looks ordinary but behaves unusually, or one who looks unusual but behaves normally.