Green’s Dictionary of Slang

schiz (out) v.

also schitz, schiz, schizz out, shitz, skitz, skiz out
[schizo n.]

1. (orig. US) to go mad, to exhibit the signs of insanity; thus vtr. to drive mad, to disturb emotionally .

[US]Eble Campus Sl. Mar. 5: schized or schized out – to go crazy or insane; to have a mental breakdown.
[US]C. McFadden Serial 32: She thought he’d schizzed out completely.
[US]Eble Campus Sl. Nov. 8: stress out [...] also schitz out.
[US]D. Jenkins You Gotta Play Hurt 57: Shag Monti [...] babbled incessantly about the ‘stone foxes’ in town and how he was ‘schizzing out’ from all things ‘radical’ .
B. Salisbury on Urban Dict. 🌐 skitzing to go crazy or utterly insane due to stress or another incident. Next step up from tripping; implying skitzophrenia. I have an essay due in thirty minutes and I’m skitzing so bad I just want to set my head on fire!
Sioux City Jrnl (IA) 4 Apr. A8/4: Kauffman [...] said the two were high on methamphetamine [...] and were ‘schitzing out.’ ‘I was starting to, like starting schitzing, but he was a lot worse’.
[US]Indiana Gaz. (PA) 13 June 30/2: ‘There is no identity crisis [...] we’re not worried about cracking up or schitzing out’.
[Aus]L. Redhead Cherry Pie [ebook] It was Holly, a skitzed out look in her eye, holding an axe.
[US](con. 1962) J. Ellroy Enchanters 13: My reverie unraveled. The dump job schizzed me.

2. (US drugs) to hallucinate from crack cocaine use.

[US]L. Pettiway Workin’ It 30: You schitz longer than the high lasts [...] you don’t schitz while you’re rushing, you know. [Ibid.] 134: People shitz all kinds of ways when they’re sitting up in hit houses. [...] What you call it – hallucinating.

3. (US) to become emotional, tense.

[US]Eble Campus Sl. Mar. 6: skiz out – to become intensely excited.
[US](con. 1964–8) J. Ellroy Cold Six Thousand 57: He said ‘Arden.’ Ward schizzed. He called Ward on Ruby. Ward played it oblique.