1. [mid–late 19C] unheated spirits; usu. as cold without
2. [1980s+] (US black) a cigarette end [? it is no longer alight].
[mid–late 19C] spirits, unheated and without an additive, e.g. sugar (cf. hot with under hot n.).
SE in slang uses
1. [19C+] to have a venereal disease.
2. [mid-19C–1910s] to be in debt; thus have a very bad cold, to leave one’s lodgings without paying the rent.