Green’s Dictionary of Slang

twasted adj.

[twatted adj. + wasted adj. (4)]

intoxicated by drink or drugs.

‘Christina D’s Drunken Column’ at [Internet] The three of us sat in a circle and took shot after shot passing the bottle around the circle! [...] By the time i was abliterated [sic] i had taken 8 ‘tina shots.’ That totals up to be 18 or 19 regular shots of VODKA! I was twasted!!
[US]E-40 F/ Young Mugzi ‘Like A Jungle’ [lyrics] Sparkin up a bunch of commotion and static it’s a habit / Bloated twasted loaded tilted when I roll it.