Green’s Dictionary of Slang

sko n.

[abbr. skanky adj. + ho n.1 ; compare skoochie n.]

(US black/campus) a disgusting, promiscuous woman.

Online Sl. Dict. 🌐 sko n 1. a promiscuous female. Abbrevation for ‘skanky hoe.’ (‘That girl is such a sko!’).