Green’s Dictionary of Slang

Main Streeter n.

[Main Street, small-town America, f. the novel of that name by Sinclair Lewis (1920) ]

a provincial, small-town person.

[US]Webster’s New International Dict. (2nd edn).
[UK]Sat. Rev. Lit. (US) 6 Oct. 8/2: His books started some Americans laughing at others and made it possible for people to realize that somebody else was a Main Streeter [DA].
[US]Time 27 Jan. 4/3: It has raised the hope of this Mainstreeter from Podunk to its highest ebb since the era of Wendell Willkie’s ‘One World’ [DA].